There are actually a whole bunch of studies in rats showing that Garcinia Cambogia consistently leads to significant weight loss (3, 4, 5, 6). However, what works in rats doesnt always work in humans. Bottom Line: Studies in rats show that the active ingredient in Garcinia Cambogia can inhibit a fat producing enzyme called Citrate Lyase and increase serotonin levels, leading to significant weight loss.

A Look at Some Human Studies Fortunately, I also found several human studies on Garcinia Cambogia. All of these studies are so-called randomized controlled trials, which are the gold standard of scientific experiments in humans. The biggest of the studies included 135 overweight individuals, which were split into two groups (7): Treatment group: 1 gram of Garcinia Cambogia Extract, 3 times per day, taken 30 minutes before meals.

Placebo group: The other group took dummy pills (placebo). Both groups also went on a high-fiber, low calorie diet. These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al. 1998 As you can see, both groups lost weight. But the group taking Garcinia Cambogia extract actually lost less weight (3.

2 kg 7 pounds) than the placebo group (4. 1 kg 9 pounds). The researchers also looked at body fat percentage. The placebo group lost 2. 16, while the group taking Garcinia Cambogia lost only 1.