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The analysis revealed that some statistically significant weight loss occurred, but the magnitude of the effect is small datlng the clinical relevance is uncertain. They also found that gastrointestinal adverse events were twice as likely in the hydroxycitric acid group as in the placebo group.

When you are considering the potential benefits of products look for meta-analysis studies that take in all the sound research available. One-off studies that get a significant result are not evidence of anything.

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Woman Smiling and Holding a Supplement I managed to find several research studies on Garcinia Cambogia, in both animals and humans. According to some studies in rats, it can inhibit a fat producing enzyme called Citrate Lyase, making it more difficult for the body to produce 440 out of carbohydrates (1).

Other rat studies show increased levels of the neurotransmitter serotonin. This could theoretically lead to reduced appetite and cravings (2). There are actually a whole bunch of studies in rats showing that Garcinia Cambogia consistently leads to significant weight loss (3, 4, 5, 40 dating 24.

However, what works in rats doesnt always work in humans. Bottom Line: Studies in rats show daying the active ingredient in Garcinia Cambogia can inhibit a fat producing enzyme called Citrate Lyase and increase serotonin levels, leading to significant weight loss. A Look at Some Human Studies Fortunately, I also found several human studies on Garcinia Cambogia.

All of these studies are so-called randomized controlled trials, which are the gold standard of scientific experiments in humans. The biggest of the studies included 135 overweight individuals, which were split into two groups (7): Treatment group: 1 gram of Garcinia Cambogia Extract, 3 times per day, taken 30 minutes before meals. 4 group: The other group took dummy pills (placebo).

Both groups also went on a high-fiber, low calorie diet. These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al.

1998 As you can see, both groups lost weight. But the group taking Garcinia Cambogia extract actually lost less weight (3. 2 kg 7 pounds) than the placebo group (4. 1 kg 9 pounds). The researchers also looked at body fat percentage.

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According to some studies in rats, it can inhibit a fat producing enzyme called Citrate Lyase, making it more difficult for the body to produce fat out of carbohydrates (1).

Other rat studies show increased levels of the neurotransmitter serotonin. This could theoretically lead to reduced appetite and cravings (2). There are actually a whole bunch of studies in rats showing that Garcinia Cambogia consistently leads to significant weight loss (3, 4, 5, 6). However, what works in rats doesnt always work in humans.

Bottom Line: Studies in rats show that the active ingredient in Garcinia Cambogia can inhibit a fat producing enzyme called 40 dating 24 Lyase and increase serotonin levels, leading to significant weight loss.

A Look at Some Human Studies Fortunately, I also found several human studies on Garcinia Cambogia. All of these studies are so-called randomized controlled trials, which are the gold standard of scientific experiments in humans. The biggest of the studies included 135 overweight individuals, which were split into two groups (7): Treatment group: 1 gram of Garcinia Cambogia Extract, 3 times per day, taken 30 minutes before meals. Placebo group: The other group took dummy pills (placebo).

Both groups also went on a high-fiber, low calorie diet. These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al. 1998 As you can see, both groups lost weight. But the group taking Garcinia Cambogia extract actually lost less weight (3.

2 kg 7 pounds) than the placebo group (4. 1 kg 9 pounds). The researchers also looked at body fat percentage. The placebo group lost 2. 16, while the group taking Garcinia Cambogia lost only 1.

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They also offer special deals where you can get free bottles if you buy several at a time. Garcinia cambogia is a fruit grown across India and Southeast Asia and it is used there as a food and its rinds are used in some traditional recipes of south India.

It used to be an obscure hard-to-find ingredient, but recently the Internet has exploded with websites selling weight loss products based on an extract of the fruit and it even got some decidedly hucksterish treatment from Dr.

Oz, a TV personality made famous by Oprah Winfrey. The fruit is known in India as gambooge. It is apparently also an ingredient in some weight loss products as hydroxycitric acid. Oz promoted it and continues to assert that garcinia cambogia is 40 dating 24 effective aid to weight loss. The claims for weight loss are nothing short of outlandish and there is real science that suggests the whole thing is a hoax. Studies that claim to have found weight loss were carried out on animals.

Studies involving humans are for the most part badly designed. A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association.

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