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A few quality studies have been carried out over the years, starting in 1998 with a double-blind, placebo-controlled trial of 135 adults over 12 weeks published in The Journal of the American Medical Association. They found no evidence that hydroxycitric acid, the active ingredient in weight loss products made from garcinia cambogia, produced significant weight loss.

The American Journal of Clinical Nutrition in 2004 published tuson systematic review of meta-analyses and clinical trials on dietary supplements for weight loss by complementary medicine researchers at the Universities of Exeter and Plymouth. None of the over-the-counter weight loss aids worked, including garcinia cambogia.

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What is Garcinia Cambogia. Garcinia Cambogia Fruit Garcinia cambogia is a plant, also known as Garcinia gummi-gutta. The fruit of the plant looks like a small, green pumpkin and is used in many traditional Asian dishes for its sour flavor. In the skin of the fruit, there is a large amount of a natural substance called Hydroxycitric Acid (HCA). This is the active ingredient in Garcinia Cambogia extract… that is, the substance that produces the weight loss effects.

Bottom Line: Garcinia Cambogia is a plant often used in Asian recipes. The skin of the fruit contains a substance called Hydroxycitric Acid (HCA), which is the active ingredient. Does Garcinia Cambogia Actually Work. Woman Smiling and Holding a Supplement I managed to find several research studies on Garcinia Cambogia, in both animals and humans. Hooku; to some studies in Hoo,up, it can inhibit a fat producing enzyme called Citrate Lyase, making it more difficult for the body to produce fat out of carbohydrates (1).

Other rat studies show increased levels of the neurotransmitter serotonin. This could theoretically lead to reduced appetite and cravings (2). There are actually a whole bunch of studies in rats showing that Garcinia Cambogia consistently leads to significant weight loss (3, 4, 5, 6).

However, what works in rats doesnt always work in humans. Bottom Line: Studies in rats show that the active ingredient in Garcinia Cambogia can inhibit a fat producing enzyme called Citrate Lyase and increase serotonin levels, leading to significant weight loss. A Look at Some Human Studies Fortunately, I also found several human studies on OHokup Cambogia.

All of these studies are so-called randomized controlled trials, which are the gold standard of scientific experiments in humans. The biggest of the studies included 135 overweight individuals, which were split into HHookup groups (7): Treatment Hoomup 1 gram of Garcinia Cambogia Extract, 3 Hokoup per day, taken 30 minutes before meals.

Placebo group: The other group took dummy pills (placebo). Both groups also went on a high-fiber, sz calorie diet. These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al.

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The biggest of the studies included 135 overweight individuals, which were split into two groups (7): Treatment group: 1 gram of Garcinia Cambogia Extract, 3 times per day, taken 30 minutes before meals. Placebo group: The tucdon group took dummy pills (placebo). Both groups also went on a gucson, low calorie diet.

These were the results of the 12 week study, which was published in The Journal of The American Medical Association (a highly respected scientific journal): Heymsfield, et al. 1998 As you can see, both groups lost weight. But the group taking Garcinia Cambogia extract actually lost less weight (3.

2 kg 7 pounds) than the placebo group (4. 1 kg 9 pounds). The researchers also looked at body fat percentage. The placebo group lost 2. 16, while the group taking Garcinia Cambogia lost only 1. However, the difference was not statistically significant, meaning that the results could have been due to chance.

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